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gcomputation - Causal Inference by using G-Computation

Several functions and S3 methods for G-computation and emulation of clinical trials. It allows for flexible estimation of the outcome model, especially penalized regressions (Lasso, Ridge, or Elasticnet) for binary, continuous, counting, or right-censored time-to-event outcomes. Average treatment effect among the entire population (ATE) or among the treated population (ATT) can be estimated. The method for time-to-events is described by Chatton et al. (2020) <doi:10.1038/s41598-020-65917-x>. For a binary outcome, details are available in the paper proposed by Chatton et al. (2022) <doi:10.1177/09622802211047345>.

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biostatisticscausal-inferenceconfounders

5.02 score 7 stars 255 downloads

RISCA - Causal Inference and Prediction in Cohort-Based Analyses

Numerous functions for cohort-based analyses, either for prediction or causal inference. For causal inference, it includes Inverse Probability Weighting and G-computation for marginal estimation of an exposure effect when confounders are expected. We deal with binary outcomes, times-to-events, competing events, and multi-state data. For multistate data, semi-Markov model with interval censoring may be considered, and we propose the possibility to consider the excess of mortality related to the disease compared to reference lifetime tables. For predictive studies, we propose a set of functions to estimate time-dependent receiver operating characteristic (ROC) curves with the possible consideration of right-censoring times-to-events or the presence of confounders. Finally, several functions are available to assess time-dependent ROC curves or survival curves from aggregated data.

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4.96 score 4 stars 1 dependents 51 scripts 519 downloads

survivalmodels - Models for Survival Analysis

Implementations of classical and machine learning models for survival analysis, including deep neural networks via 'keras' and 'tensorflow'. Each model includes a separated fit and predict interface with consistent prediction types for predicting risk or survival probabilities. Models are either implemented from 'Python' via 'reticulate' <https://CRAN.R-project.org/package=reticulate>, from code in GitHub packages, or novel implementations using 'Rcpp' <https://CRAN.R-project.org/package=Rcpp>. Neural networks are implemented from the 'Python' package 'pycox' <https://github.com/havakv/pycox>.

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cpp

4.03 score 1 stars 72 scripts 538 downloads

survivalSL - Super Learner for Survival Prediction from Censored Data

Several functions and S3 methods to construct a super learner in the presence of censored times-to-event and to evaluate its prognostic capacities.

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3.48 score 1 stars 9 scripts 231 downloads